Introduction Cushing’s syndrome (CS) is a constellation of features associated with prolonged exposure to inappropriately high levels of plasma glucocorticoids. The most common cause of this is from exogenous glucocorticoid use. Endogenous causes of Cushing’s syndrome are rare. Classification & causes of Cushing’s Syndrome 1. ACTH-dependent Cushing’s disease Ectopic ACTH Syndrome Macronodular Adrenal Hyperplasia 2. … Read more
Introduction Hypothyroidism refers to subnormal amounts of thyroid hormones in the circulation, and the clinical features associated with it. Aetiology May be primary or secondary Primary hypothyroidism is more common and: Is probably an autoimmune disease; which may occur as a sequel to Hashimoto’s thyroiditis. Post therapeutic hypothyroidism (medical or surgical) Secondary hypothyroidism: Occurs when … Read more
Introduction Overweight and obesity increase the risk for several diseases such as hypertension, ischaemic heart disease, and diabetes mellitus. Obesity results from an imbalance between energy intake and energy expenditure. However, more recent researches, have suggested that genetics, physiological and behavioural factors also play significant roles in the aetiology of obesity. Management of weight disorders … Read more