Sickle Cell Disease in Children

Introduction Sickle cell disease is a group of inherited red blood cell disorders with one abnormal haemoglobin called Haemoglobin S and another that is also abnormal in the rbc. Haemoblobin molecule is unusually sensitivity to low oxygen tension making it to denature affecting its shape to sickle and its oxygen carrying capacity. If the other … Read more

Vitamin A Deficiency

Introduction Vitamin A was the first fat-soluble vitamin to be discovered. It comprises a family of compounds called the retinoids. In nature, the active retinoids occur in 3 forms – Alcohol (retinol), aldehyde (retinal or retinaldehyde) and acid (retinoic acid). In the human body, retinol is the predominant form, and 11-cis-retinol is the active form. … Read more

Poliomyelitis

Introduction Poliomyelitis is an acute infectious disease of humans (particularly children) caused by any of three serotypes of poliovirus P1, P2, and P3. Immunity to one serotype does not confer immunity to others. It occurs in many regions of the developing countries. The global polio eradication initiative was launched in 1988. In 15 years, the … Read more

Measles (Rubeola)

Introduction Measles is an acute viral infection caused by an RNA virus of the genus of Morbillivirus which is in the family Paramyxoviridae. Only one serotype is known. Measles is endemic throughout the world. It is a major contributor to childhood mortality. There is however, a 79% reduction in deaths from measles due to the … Read more